En la compatibilidad con ASP.NET no se admiten otros protocolos que no sean HTTP/HTTPS. Quite el extremo 'X' o deshabilite la compatibilidad con ASP.NET para la aplicación.
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English version
Protocols other than HTTP/HTTPS are not supported under ASP.NET compatibility. Remove the endpoint 'X' or disable ASP.NET compatibility for the application.
.Net Framework